Metabolomics profile of Japanese female patients with restricting-type anorexia nervosa

In this study, the serum metabolic profiles of 10 female patients with restricting type anorexia nervosa (ANR) were compared to those age-matched healthy controls. While levels amino acids lower among than controls, uremic toxins, including p-cresyl sulfate (PCS), indole-3-acetic acid, and phenyl sulfate, higher in ANR patients. The PCS correlated positively abundance Clostridium coccoides group or C. leptum subgroup feces patients, but not Collectively, these results indicate that differ from women terms both decreased acid increased toxins. Gut microbes may be involved such an increase